Publications
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As leaders in finding new ways to help treat treatment-resistant depression we’ve published a lot of articles over the years. Here are some of them…
Combination therapy with transcranial magnetic stimulation and ketamine for treatment-resistant depression: A long-term retrospective review of clinical use
authors: Steven R. D. Best, Dan G. Pavel, and Natalie Haustrup
publication: Heliyon, 2019
Brain SPECT as an Imaging Biomarker for Evaluating Effects of Novel Treatments in Psychiatry: A Case Series
authors: Steven R. D. Best, Natalie Haustrup and Dan G. Pavel
publication: frontiers in Psychiatry, 2022
doi: 10.3389/fpsyt.2021.713141
This retrospective clinical review examined the safety and effectiveness of a novel combination therapy—transcranial magnetic stimulation (TMS) with ketamine analgesia (CTK)—for patients with treatment-resistant depression (TRD). Twenty-eight patients who had not responded to other treatments received high-output TMS and biomarker-guided ketamine infusions. The study found a significant reduction in depression severity, as measured by the Clinical Global Impression (CGI) scale, which was sustained for two years after treatment. The combination allowed for higher TMS intensities than usual, with no major adverse effects. The authors conclude that CTK can be a promising long-term therapy for TRD.
The article "Brain SPECT as an Imaging Biomarker for Evaluating Effects of Novel Treatments in Psychiatry–A Case Series" explores the use of Single Photon Emission Computed Tomography (SPECT) as a functional brain imaging tool to assess and monitor the effects of novel treatments in patients with complex neuropsychiatric conditions. The study presents six case studies where SPECT imaging was used to evaluate the efficacy of treatments such as combination transcranial magnetic stimulation with ketamine infusions (CTK), hyperbaric oxygen therapy (HBOT), and perispinal administration of etanercept (PSE). The findings suggest that SPECT imaging can serve as a valuable biomarker for monitoring clinical changes and guiding treatment decisions in psychiatry.
Awards
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2022
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2021
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2019
2020
Awards & Recognitions
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It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more.
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It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more.
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It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more.
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It all starts with an idea
It all begins with an idea. Maybe you want to launch a business. Maybe you want to turn a hobby into something more.
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